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  1. Oct 08, 2014
  3. Sep 02, 2014
    • Vermaat's avatar
      Add ALT_REF_LOCI contigs to GRCh38/hg38 assembly · 3a90ba40
      Vermaat authored 
      Using fetchChromSizes [1] and selecting *Download the full sequence report*
from the NCBI assembly overview [2] we can generate a mapping from UCSC
chromosome names to accession numbers:

    ./fetchChromSizes hg38 > human.hg38.genome
    for contig in $(cut -f 1 human.hg38.genome | grep 'alt$'); do
        code=$(echo $contig | cut -d _ -f 2 | sed 's/v/./')
        echo -n $contig$'\t'
        grep $code GCF_000001405.26.assembly.txt | cut -f 7
    done > alt_chrom_names.mapping

Generate the JSON dictionary entries:

    >>> import json
    >>> entries = []
    >>> for line in open('alt_chrom_names.mapping'):
    ...     chr, acc = line.strip().split()
    ...     entries.append({'organelle': 'nucleus',
    ...                     'name': chr,
    ...                     'accession': acc})
    ...
    >>> print json.dumps(entries, indent=2)
    [
      {
        "organelle": "nucleus",
        "name": "chr12_KI270837v1_alt",
        "accession": "NT_187588.1"
      },
      {
        "organelle": "nucleus",
        "name": "chr13_KI270842v1_alt",
        "accession": "NT_187596.1"
      },
      ...
    ]

[1] http://hgdownload.cse.ucsc.edu/admin/exe/linux.x86_64/fetchChromSizes
[2] ftp://ftp.ncbi.nlm.nih.gov/genomes/ASSEMBLY_REPORTS/All/GCF_000001405.26.assembly.txt
      3a90ba40
    • Vermaat's avatar
      Add GRCh38 (hg38) assembly · 2cc108a8
      Vermaat authored
      2cc108a8
  5. Aug 28, 2014
  7. Apr 23, 2014
    • Vermaat's avatar
      Move to Sphinx for developer documentation · 2f33e62c
      Vermaat authored 
      This is quite a large commit, touching many things related to developer
documentation. It is all focussed on getting as much of this as possible
into the new Sphinx-based documentation.

Some highlights:

- Start Sphinx-based developer documentation, including fairly complete
  instructions for installation and configuration.
- Remove epydoc API docs.
- Rework some docstrings to conform to reStructuredText, so they can be
  used in the API docs generated by Sphinx.
- Move all of the top-level text files to reStructuredText so they can
  linked from the Sphinx-based docs and for consistency.
- Remove many obsolete things from the extras/ directory, including old
  installation scripts and migrations.

Many of the installation related documentation and scripts are removed
or adapted in light of the new automated deployment using Ansible.
      2f33e62c
  9. Feb 17, 2014
    • Vermaat's avatar
      Rename organelle_type to organelle in chromosome model · 352c590b
      Vermaat authored 
      Also, the value for nuclear chromosomes is now `nucleus` instead of
`chromosome` for better alignment with the other value `mitochondrion`.

Note that I did not bother to make an Alembic migration for this, since
we don't have any installations besides my own yet anyway.
      352c590b
  11. Jan 25, 2014
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  59. Jul 23, 2012