This tool normalizes a VCF file annotated with the Variant Effect Predictor (VEP).
This tool modifies a VCF file annotated with the Variant Effect Predictor (VEP).
Since the VEP does not use INFO fields to annotate, but rather puts all its annotations in one big string inside a "CSQ" INFO tag it is necessary to normalize it.
Since the VEP does not use INFO fields to annotate, but rather puts all its annotations in one big string inside a "CSQ" INFO tag it is necessary to normalize it.
This normalizer will use the information in the CSQ header to create INFO fields for each annotation field.
Tool will parse the information in the CSQ header to create INFO fields for each annotation field. Tool has two modes: `standard` and `explode`.
It has two modes: `standard` and `explode`. The `standard` mode will produce a VCF according to the VCF specification.
The `standard` mode will produce a VCF according to the VCF specification.
This means that every VEP INFO tag will consist of the comma-separated list of values for each transcript.
This means that every VEP INFO tag will consist of the comma-separated list of values for each transcript.
In case the value is empty, the VEP INFO tag will not be shown for that specific record
In case the value is empty, the VEP INFO tag will not be shown for that specific record
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@@ -20,6 +21,7 @@ The CSQ tag is by default removed from the output VCF file. If one wishes to ret
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@@ -20,6 +21,7 @@ The CSQ tag is by default removed from the output VCF file. If one wishes to ret