From 4ee4ee23ac0abdcf8a9ab67d1275c971a81374a4 Mon Sep 17 00:00:00 2001 From: Ioannis Moustakas <i.moustakas@lumc.nl> Date: Thu, 14 Jul 2016 14:11:28 +0200 Subject: [PATCH] Improve phrasing --- docs/tools/VepNormalizer.md | 8 +++++--- 1 file changed, 5 insertions(+), 3 deletions(-) diff --git a/docs/tools/VepNormalizer.md b/docs/tools/VepNormalizer.md index a7cc59125..e5624e9a5 100644 --- a/docs/tools/VepNormalizer.md +++ b/docs/tools/VepNormalizer.md @@ -3,11 +3,12 @@ VepNormalizer Introduction ------------ -This tool normalizes a VCF file annotated with the Variant Effect Predictor (VEP). +This tool modifies a VCF file annotated with the Variant Effect Predictor (VEP). Since the VEP does not use INFO fields to annotate, but rather puts all its annotations in one big string inside a "CSQ" INFO tag it is necessary to normalize it. -This normalizer will use the information in the CSQ header to create INFO fields for each annotation field. -It has two modes: `standard` and `explode`. The `standard` mode will produce a VCF according to the VCF specification. +Tool will parse the information in the CSQ header to create INFO fields for each annotation field. Tool has two modes: `standard` and `explode`. + +The `standard` mode will produce a VCF according to the VCF specification. This means that every VEP INFO tag will consist of the comma-separated list of values for each transcript. In case the value is empty, the VEP INFO tag will not be shown for that specific record @@ -20,6 +21,7 @@ The CSQ tag is by default removed from the output VCF file. If one wishes to ret Example --------- +Help menu: ~~~ bash biopet tool VepNormalizer -h -- GitLab