Mutalyzer Restriction site analysis of RefSeq transcripts should be limited to exons
Created by: mutalyzerbot
Original ticket: https://humgenprojects.lumc.nl/trac/mutalyzer/ticket/65 Original date: 2011/10/11 Original reporter: p DOT taschner AND lumc DOT nl
Mutalyzer reports restriction sites created or deleted by the variant checked. In case of RefSeq transcripts with exon location annotation, the recognition sites of the enzymes shown should be completely contained within the range of an exon. In case of RefSeq transcripts without exon location annotation, the following warning should be issued below the heading "Effects on Restriction sites": Warning: restriction sites spanning exon-exon boundaries may be shown for RefSeq transcripts without exon location annotation.