Create new Redis connection when REDIS_URI changes

When the REDIS_URI configuration setting is changed, the Redis
client should be reconfigured with a new connection pool, just
like we do with the database.

It appears redis-py manages the connection pool by itself and
doesn't expose ways to explicitely destroy it or close all
connections (this is done automatically when all connections
loose scope).

This fix ensures that the unit tests don't accidentally work on
the Redis database configured in MUTALYZER_SETTINGS, which was
quite an unfortunate bug.

Remove debug statement

Add protein_to_transcript in separate ncbi module

Jeroen F.J. Laros authored 9 years ago and Vermaat committed 9 years ago

Existing `transcript_to_protein` is factored out into a separate
`mutalyzer.ncbi` module.

Add Ter as a valid AA in the HGVS grammar

Previously, the `PSubst` rule did not register `MutationType`, so it
was a bit awkward how to check for a `p.` substitution. We can now:

    >>> grammar.parse('NP_00011.1:p.Asp23Tyr').RawVar.MutationType
    'subst'

Refactor unit tests using py.test

Especially lxml takes very long to install. By specifying the `-O0`
compiler flag this is reduced by more than half.

The actual unit tests are slightly slower with the non-optimized
C modules, but we have a netto win.

Travis CI updates

Release 2.0.13

Fix query bug in update transcript-protein links

Test database migrations

Push to release branch requires passing status checks

Release 2.0.12

Fix transcript protein link query