Modified the NBIC poster, mainly rephrasing.

Added affiliations to the list of authors in the ESHG abstract.


git-svn-id: https://humgenprojects.lumc.nl/svn/mutalyzer/trunk@517 eb6bd6ab-9ccd-42b9-aceb-e2899b4a52f1

doc/Poster_24_25-04-12_NBIC_Mutalyzer2/poster.bbl

@@ -2,7 +2,7 @@
 
 \bibitem{HGVS}
 {Human Genome Variation Society}.
-\newblock \begin{small}\texttt{http://www.hgvs.org/}\end{small}.
+\newblock \begin{small}\texttt{http://www.hgvs.org/mutnomen/}\end{small}.
 
 \bibitem{LRG}
 R.~Dalgleish and et~al.

doc/Poster_24_25-04-12_NBIC_Mutalyzer2/poster.tex

@@ -30,12 +30,12 @@
 
       \vspace{1cm}
 
-      Initial construction of variant descriptions, however, requires comparison
-      of the reference sequence and the variant sequence and basic knowledge of
-      the HGVS recommendations. With the arrival of long read sequencers (e.g.
-      PacBio) and the rise of sophisticated variant callers, the chance of
-      finding a complex variant increases and so does the need to describe these
-      variants.
+      Initial construction of variant descriptions, however, requires
+      comparison of reference sequences and variant sequences and basic
+      knowledge of the HGVS recommendations. With the arrival of long read
+      sequencers (e.g., PacBio) and the rise of sophisticated variant callers,
+      the chance of finding complex variants increases and so does the need to
+      describe these variants.
 
       \vspace{1cm}
 
@@ -50,7 +50,7 @@
 
       \vspace{1cm}
 
-      To aid in the construction of a variant description, Mutalyzer includes
+      To aid in the construction of variant descriptions, Mutalyzer includes
       the Name Generator (Fig.~\ref{figure:namegenerator}), alleviating the
       need for knowledge of the HGVS recommendations. However, comparison of
       reference and variant sequences still has to be done by the user and can
@@ -60,11 +60,11 @@
       The new Description Extractor can be used to automatically construct
       variant descriptions according to the HGVS recommendations by sequence
       comparison. The algorithm closely follows the human approach to
-      describe a variant. It will first find the ``area of change'' and then
+      describe variants. It will first find the ``area of change'' and then
       finds the largest overlap between the original area and the area in the
       variant sequence. This process is repeated until  the smallest
-      description is found. This not only helps clinicians to generate the
-      correct description, but its implementation also allows automation of
+      description is found. This not only helps clinicians to generate
+      correct descriptions, but its implementation also allows automation of
       the description process.
 
       \vspace{1cm}
@@ -109,12 +109,12 @@
 
     }
     \nextColumn
-    \colorBlock{WhiteBg}{Conclusions}{1}{
+    \colorBlock{WhiteBg}{Conclusions and further research}{1}{
       With this proof-of-concept we have shown that it is feasible to
       automatically generate correct variant descriptions following the HGVS
-      recommendations based on a comparison of the original sequence and the
-      observed sequence. The implementation relieves the user from the often
-      complex task of manually creating a description and guarantees
+      recommendations based on comparisons of reference sequences and 
+      observed sequences. The implementation relieves the user from the often
+      complex task of manually creating descriptions and guarantees
       conformity to HGVS.
 
       \vspace{1cm}
@@ -122,8 +122,8 @@
       As future work we plan to implement description extraction from reference
       sequences either identified by accession number or manually uploaded.
       This will enable, for example, easy construction of descriptions for the
-      difference between different versions of reference sequence, either
-      genomic or transcript.
+      difference between different versions of genomic or transcript reference
+      sequences.
     }
     \colorBlock{BlueBg}{Name Checking}{1}{
       \begin{figure}

doc/abstractESHG/abstract.tex

@@ -2,9 +2,17 @@
 \usepackage{fullpage}
 
 \newcommand{\superscript}[1]{\ensuremath{^{\textrm{#1}}}}
+\newcommand{\shl}{\hfill\phantom{.}}
 \frenchspacing
 
-\author{J.F.J. Laros \and M. Vermaat \and J.T. den Dunnen \and P.E.M. Taschner}
+\author{J.F.J. Laros$^{1,2}$ \and M. Vermaat$^{1,2}$ \and J.T. den Dunnen$^1$
+  \and P.E.M. Taschner$^1$\\
+  \small $1$ Department of Human Genetics, Leiden Genome Technology Center,
+    Leiden University Medical Center,\shl\\
+  \small \,\ \ Leiden, The Netherlands\shl\\
+  \small $2$ Netherlands Bioinformatics Centre\shl\\
+  \texttt{J.F.J.Laros@lumc.nl}
+  }
 \title{Generating complex descriptions of sequence variants using HGVS
   nomenclature based on sequence comparison.\footnote{Funded in part by the
   European Community's Seventh Framework Programme (FP7/2007-2013) under grant