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biopet.biopet
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13c61914
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13c61914
authored
8 years ago
by
Moustakas
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Improve phrasing and options description
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docs/tools/VcfFilter.md
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# VcfFilter
## Introduction
This tool filters VCF files on a number values. For example, it can filter on sample depth and/or total depth.
It can also filter out the reference calls and/or minimum number of sample passes.
For more on filtering options and how to set them, please refer to the help menu.
This tool enables a user to filter VCF files. For example on sample depth and/or total depth.
It can also be used to filter out the reference calls and/or minimum number of sample passes.
There is a wide set of options which one can use to change the filter settings.
...
...
@@ -32,19 +37,19 @@ Usage: VcfFilter [options]
Min number of samples to pass
--minAlternateDepth
,
--minBamAlternateDepth
and
--minSampleDepth
--minBamAlternateDepth
<int>
--denovoInSample
<sample>
Only
show
variants that contain unique alleles
in
compete
set
for
given sample
Only
keep
variants that contain unique alleles
in
comp
l
ete set
for
the
given sample
--mustHaveVariant
<sample>
G
iven sample
must
have
1
alternative allele
Only keep variants that
for
the g
iven sample have
an
alternative allele
--diffGenotype
<sample:sample>
G
iven samples
must
have a different genotype
--filterHetVarToHomVar
<sample:sample>
If variants
in
sample 1 are heterogeneous and alternative alleles are
homo
gene
ous
in
sample
2 variants are filtered
Only keep variands that
for
the g
iven samples have a different genotype
--filterHetVarToHomVar
<sample
1
:sample
2
>
Filter out varianst that are heterozygous
in
sample1 and
homo
zyg
ous
in
sample
2
--filterRefCalls
Filter
when there are only
ref calls
Filter
out
ref calls
--filterNoCalls
Filter
when there are only
no calls
Filter
out
no calls
--minQualScore
<value>
Min qual score
Filter out variants with Min qual score below threshold
~~~
To run the tool:
...
...
@@ -54,4 +59,4 @@ biopet tool VcfFilter --inputVcf myInput.vcf \
~~~
## Output
The output is a vcf file containing the filters specified values.
\ No newline at end of file
The output is a vcf file containing the values that pass the user-defined filtering options
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