"The lesson was based on previous material by [Wibowo Arindrarto](mailto://w.arindrarto@lumc.nl) and Martijn Vermaat.\n",
"The lesson was based on previous material by [Guy Allard](mailto://w.g.allard@lumc.nl), [Wibowo Arindrarto](mailto://w.arindrarto@lumc.nl) and Martijn Vermaat.\n",
/references=[Reference(title='The RNA helicase DDX39B and its paralog DDX39A regulate androgen receptor splice variant AR-V7 generation', ...), Reference(title='Identification of DDX39A as a Potential Biomarker for Unfavorable Neuroblastoma Using a Proteomic Approach', ...), Reference(title='Up-regulation of DDX39 in human malignant pleural mesothelioma cell lines compared to normal pleural mesothelial cells', ...), Reference(title='The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts', ...), Reference(title='Clinical proteomics identified ATP-dependent RNA helicase DDX39 as a novel biomarker to predict poor prognosis of patients with gastrointestinal stromal tumor', ...), Reference(title='The closely related RNA helicases, UAP56 and URH49, preferentially form distinct mRNA export machineries and coordinately regulate mitotic progression', ...), Reference(title='Hcc-1 is a novel component of the nuclear matrix with growth inhibitory function', ...), Reference(title='Growth-regulated expression and G0-specific turnover of the mRNA that encodes URH49, a mammalian DExH/D box protein that is highly related to the mRNA export protein UAP56', ...), Reference(title='Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region', ...), Reference(title='The BAT1 gene in the MHC encodes an evolutionarily conserved putative nuclear RNA helicase of the DEAD family', ...)]
/comment=REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from DA432925.1, BC001009.2 and
BM792110.1.
This sequence is a reference standard in the RefSeqGene project.
On Oct 14, 2010 this sequence version replaced NM_005804.2.
Summary: This gene encodes a member of the DEAD box protein family.
These proteins are characterized by the conserved motif
Asp-Glu-Ala-Asp (DEAD) and are putative RNA helicases. They are
implicated in a number of cellular processes involving alteration
of RNA secondary structure, such as translation initiation, nuclear
and mitochondrial splicing, and ribosome and spliceosome assembly.
Based on their distribution patterns, some members of the DEAD box
protein family are believed to be involved in embryogenesis,
spermatogenesis, and cellular growth and division. This gene is
thought to play a role in the prognosis of patients with
gastrointestinal stromal tumors. A pseudogene of this gene is
present on chromosome 13. Alternate splicing results in multiple
This lesson was just a small taste of what can be done with Biopython.
I strongly recommend looking at the [Biopython 'cookbook'](http://biopython.org/DIST/docs/tutorial/Tutorial.html) to get an idea of the wide range of things that you can do with it.
%% Cell type:markdown id: tags:
The lesson was based on previous material by [Wibowo Arindrarto](mailto://w.arindrarto@lumc.nl) and Martijn Vermaat.
The lesson was based on previous material by [Guy Allard](mailto://w.g.allard@lumc.nl), [Wibowo Arindrarto](mailto://w.arindrarto@lumc.nl) and Martijn Vermaat.