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{% extends "base.html" %}
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{% set active_page = "homepage" %}
{% set page_title = "Welcome to the Mutalyzer website" %}
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{% block content %}

<p>
The aim of this program suite is to support checks of sequence variant
nomenclature according to the
<a href="http://www.hgvs.org/mutnomen/">guidelines</a> of the
<a href="http://www.hgvs.org">Human Genome Variation Society</a>.
</p>

<p>
Different interfaces are provided to collect the information necessary
for the checks:
</p>
<ul>
  <li>
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    The <a href="{{ url_for('.name_checker') }}">Name Checker</a> takes the complete sequence
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    variant description as input and checks whether it is correct.
  </li>
  <li>
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    The <a href="{{ url_for('.syntax_checker') }}">Syntax Checker</a> takes the complete
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    sequence variant description as input and checks whether the syntax
    is correct.
  </li>
  <li>
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    The <a href="{{ url_for('.position_converter') }}">Position Converter</a> can convert
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    chromosomal positions to transcript orientated positions and vice
    versa.
  </li>
  <li>
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    The <a href="{{ url_for('.snp_converter') }}">SNP converter</a> allows you to convert a
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    dbSNP rsId to HGVS notation.
  </li>
  <li>
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    The <a href="{{ url_for('.name_generator') }}">Name Generator</a> is a user friendly
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    interface that helps to make a valid HGVS variant description.
  </li>
  <li>
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    The <a href="{{ url_for('.description_extractor') }}">Description Extractor</a> allows
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    you to generate the HGVS variant description from a reference
    sequence and an observed sequence.
  </li>
  <li>
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    The <a href="{{ url_for('.reference_loader') }}">Reference File Loader</a> allows you to load and
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    use your own reference sequence.
  </li>
  <li>
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    The <a href="{{ url_for('.batch_jobs') }}">Batch Checkers</a> are interfaces that accept a
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    list of inputs. These interfaces can be used for large quantities of
    checks.
  </li>
  <li>
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    The <a href="{{ url_for('.webservices') }}">Web services</a> page provides instructions
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    for the web services.
  </li>
</ul>

<p>
GenBank sequences are retrieved from the
<a href="http://www.ncbi.nlm.nih.gov/">NCBI</a>
(<a href="http://eutils.ncbi.nlm.nih.gov/About/disclaimer.html"
>Copyright and Disclaimers</a>).
</p>

<p>
This project is sponsored by
<a href = "http://www.sun.com">SUN Microsystems</a> with server
hardware within the scope of the Academic Excellence Grant (AEG)
program (award EDUD-7832-080223-CNE).
</p>

{% endblock content %}