index.html 2.89 KB
Newer Older
1
<html>
2
  <head>
3
    <title></title>
4
5
6
  </head>
  <body>
    <div metal:define-macro="content">
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
      <center><h3>Welcome to the Mutalyzer web site</h3></center>
      <br>
      
      The aim of this program suite is to support checks of sequence variant
      nomenclature according to the 
      <a href="http://www.hgvs.org/mutnomen/">guidelines</a> of the 
      <a href="http://www.hgvs.org">Human Genome Variation Society</a>.<br>
      <br>
      <br>
      
      Different interfaces are provided to collect the information necessary
      for the checks:
      <ul>
        <li>
          The <a href = "check">Name Checker</a> takes the complete sequence
          variant description as input and checks whether it is correct.
        </li>
        <li>
          The <a href = "syntaxCheck">Syntax Checker</a> takes the complete
          sequence variant description as input and checks whether the syntax
          is correct.
        </li>
        <li>
          The <a href = "positionConverter">Position Converter</a> can convert
          chromosomal positions to transcript orientated positions and vice
          versa.
        </li>
        <li>
35
36
37
38
          The <a href = "snp">SNP converter</a> allows you to convert a
          dbSNP rsId to HGVS notation.
        </li>
        <li>
39
40
41
42
43
          The <a href = "nameGenerator">Name Generator</a> is a user friendly
          interface that helps to make a valid HGVS variant description.
        </li>
        <li>
          The <a href = "descriptionExtract">Description Extractor</a> allows
Laros's avatar
Typo.    
Laros committed
44
          you to generate the HGVS variant description from a reference
45
46
47
48
49
          sequence and an observed sequence.
        </li>
        <li>
          The <a href = "upload">Reference File Loader</a> allows you to load and
          use your own reference sequence.
50
51
52
53
54
55
        </li>
        <li>
          The <a href="batch">Batch Checkers</a> are interfaces that accept a
          list of inputs. These interfaces can be used for large quantities of
          checks.
        </li>
56
57
58
59
        <li>
          The <a href = "webservices">Webservices</a> page provides instructions
          for the webservices.
        </li>
60
61
      </ul>
      <br>
62
      <!--
63
64
65
66
      Mutalyzer <span tal:content = "structure string:${version}"></span> is
      written completely in <a href="http://www.python.org">Python</a>. The
      Python Scripting Language was chosen for good readability and therefore
      easy maintenance.<br>
67
      -->
68
69
70
71
72
73
74
75
      GenBank sequences are retrieved from the 
      <a href="http://www.ncbi.nlm.nih.gov/">NCBI</a> 
      (<a href="http://eutils.ncbi.nlm.nih.gov/About/disclaimer.html"
      >Copyright and Disclaimers</a>).<br>
      This project is sponsored by 
      <a href = "http://www.sun.com">SUN Microsystems</a> with server
      hardware within the scope of the Academic Excellence Grant (AEG)
      program (award EDUD-7832-080223-CNE).<br>
76
77
    </div>
  </body>
78
</html>