{% if not standalone %} {% extends "base.html" %} {% endif -%} Mutalyzer {{ mutalyzer_version }} — {{ page_title }}

Name Checker

{% set active_page = "name-checker" %} {% set page_title = "Name Checker" %}
{% block content %} {% if not standalone %}

Please insert the variant description using the HGVS format:

<accession number>.<version number>(<gene symbol>):<sequence type>.<variant description>

Examples: AB026906.1:c.274G>T, NG_012337.1(SDHD_v001):c.274G>T

{% if description %}
{% endif %} {% endif %}{# not standalone #} {% if description %} {% if parse_error %}

Parse error

{{ parse_error[0] }}
{{ parse_error[1] }}

The "^" indicates the position where the error occurred.

{% endif %} {% if messages %} {% for m in messages %} {% if m.class == "error" %}

{{ m.description }}

{% elif m.class == "warning" %}

{{ m.description }}

{% elif m.class == "information" %}

{{ m.description }}

{% elif m.class == "debug" %}

{{ m.description }}

{% endif %} {% endfor %} {% endif %} {% if summary == "0 Errors, 0 Warnings." %}

{{ summary }}

{% else %}

{{summary}}

{% endif %} {% if not parse_error %}
{% if visualisation %}

Overview of the raw variants

{% for i in visualisation %}

Raw variant {{ loop.index }}: {{ i[0] }}

{{ i[1] }}
{{ i[2] }}
{% endfor %} {% endif %} {% if browserLink %}

View original variant in UCSC Genome Browser

{% endif %} {% if genomicDescription %} {% if genomicDNA %}

Genomic description

{% else %}

Description relative to transcription start

(Not for use in LSDBs in case of protein-coding transcripts).

{% endif %}

{{ genomicDescription }}

{% endif %} {% if chromDescription %}

Alternative chromosomal position

{{ chromDescription }}

{% endif %} {% if descriptions %}

Affected transcripts

{% for i in descriptions %} {% if i.endswith('?') %}

{{ i }}

{% else %}

{{ i }}

{% endif %} {% endfor %} {% endif %} {% if protDescriptions %}

Affected proteins

{% for i in protDescriptions %}

{{ i }}

{% endfor %} {% endif %} {% if transcriptInfo %} {% if oldProtein %}

Reference protein

            {%- for i in oldProtein -%}
              {{-i |safe -}}
{%- endfor -%}

Protein predicted from variant coding sequence

{% if newProtein %}
              {%- for i in newProtein -%}
                {{- i|safe -}}
{%- endfor -%}
{% else %}

No change: predicted protein (not shown) equals reference protein.

{% endif %} {% if altStart %}

Protein predicted from variant coding sequence using start codon {{ altStart }}

{% if altProtein %}
                {%- for i in altProtein -%}
                  {{- i|safe -}}
{%- endfor -%}
{% else %}

No change: predicted protein (not shown) equals reference protein.

{% endif %} {% endif %} {% endif %} {% endif %}{# transcriptInfo #} {% if restrictionSites %}

Effects on Restriction sites

{% for i in restrictionSites %} {% endfor %}
Raw variant Created Deleted
{{ loop.index }} {% for j in i[0] %} {{ j }}{{ ',' if not loop.last }} {% endfor %} {% for j in i[1] %} {{ j }}{{ ',' if not loop.last }} {% endfor %}
{% endif %} {% if extractedDescription %}

Experimental services

Genomic description: {{ extractedDescription }}

{% endif %}
{# class="col-md-8 name-checker-left-column" #}
{% if transcriptInfo %}

Exon information

{% for i in exonInfo %} {% for j in i %} {% endfor %} {% endfor %}
Number Start (g.) Stop (g.) Start {{ '(c.)' if transcriptCoding else '(n.)' }} Stop {{ '(c.)' if transcriptCoding else '(n.)' }}
{{ loop.index }}{{ j }}
{% if transcriptCoding %}

CDS information

g. c.
Start {{ cdsStart_g }} {{ cdsStart_c }}
Stop {{ cdsStop_g }} {{ cdsStop_c }}
{% endif %} {% endif %}{# transcriptInfo #} {% if reference_filename and not standalone %}

Links

Download this reference sequence file: {{ reference_filename }}

{% endif %}
{# class="col-md-4" #}
{# class="row" #}

{% if legends %}

Legend

{% for i in legends %} {% for j in i %} {% endfor %} {% endfor %}
Name ID Locus tag Product Link method
{{ j if j else '' }}
{% endif %}
{% endif %}{# not parse_error #} {% endif %}{# description #} {% endblock content %}
{% if piwik %} {% endif %}