diff --git a/public/biopet-tools/src/main/scala/nl/lumc/sasc/biopet/tools/VcfFilter.scala b/public/biopet-tools/src/main/scala/nl/lumc/sasc/biopet/tools/VcfFilter.scala
index 0c3728d8af976217f67ced8aa06a220cd8e74cd4..cffe91f625699a517d0a7b07a60cd171d805917f 100644
--- a/public/biopet-tools/src/main/scala/nl/lumc/sasc/biopet/tools/VcfFilter.scala
+++ b/public/biopet-tools/src/main/scala/nl/lumc/sasc/biopet/tools/VcfFilter.scala
@@ -263,7 +263,7 @@ object VcfFilter extends ToolCommand {
   def minAlternateDepth(record: VariantContext, minAlternateDepth: Int, minSamplesPass: Int = 1): Boolean = {
     record.getGenotypes.count(genotype => {
       val AD = if (genotype.hasAD) List(genotype.getAD: _*) else Nil
-      if (AD.nonEmpty) AD.tail.count(_ >= minAlternateDepth) > 0 else true
+      if (AD.nonEmpty && minAlternateDepth >= 0) AD.tail.count(_ >= minAlternateDepth) > 0 else true
     }) >= minSamplesPass
   }