One can specify other options such as: `bowtie` (alignment) options, clipping and trimming options `sickle` and `cutadapt`.
Example:
```
"bowtie": {
"chunkmbs": 256, # this is a performance option, keep it high (256) as many alternative alignments are possible
"seedmms": 3,
"seedlen": 25,
"k": 5, # take and report best 5 alignments
"best": true # sort by best hit
},
"sickle": {
"lengthThreshold": 8 # minimum length to keep after trimming
},
"cutadapt": {
"error_rate": 0.2, # recommended: 0.2, allow more mismatches in adapter to be clipped of (ratio)
"minimum_length": 8, # minimum length to keep after clipping, setting lower will cause multiple alignments afterwards
"q": 30, # minimum quality over the read after the clipping in order to keep and report the read
"default_clip_mode": "both", # clip from: front/end/both (5'/3'/both). Depending on the protocol. Setting `both` makes clipping take more time, but is safest to do on short sequences such as smallRNA.
"times": 2 # in cases of chimera reads/adapters, how many times should cutadapt try to remove am adapter-sequence