diff --git a/CHANGELOG.md b/CHANGELOG.md index bcdcc6f41972cc47859927af8753ce90b508e931..ddc608586ed01e48e161195aefa83e3b4d0ea394 100644 --- a/CHANGELOG.md +++ b/CHANGELOG.md @@ -11,6 +11,7 @@ that users understand how the changes affect the new version. version 1.0.0-dev --------------------------- ++ VarDict: Add user definable flags (-M, -A, -Q, -d, -v, -f) to the paired VCF filtering script. + Cutadapt: If the output is a gzipped file, compress with level 1 (instead of default 6). + Cutadapt: Fix issues with read2output when using single-end reads. + Add feature type, idattr and additional attributes to htseq-count. diff --git a/vardict.wdl b/vardict.wdl index 069d8661d516843d9bae850e2ff3229216e84633..69a5441c22f47afccf011bddf98fb4888c10c989 100644 --- a/vardict.wdl +++ b/vardict.wdl @@ -20,10 +20,12 @@ task VarDict { Int endColumn = 3 Int geneColumn = 4 - Float? mappingQuality = 20 - Int? minimumTotalDepth = 8 - Int? minimumVariantDepth = 4 - Float? minimumAlleleFrequency = 0.02 + Boolean outputCandidateSomaticOnly = true + Boolean outputAllVariantsAtSamePosition = true + Float mappingQuality = 20 + Int minimumTotalDepth = 8 + Int minimumVariantDepth = 4 + Float minimumAlleleFrequency = 0.02 Int threads = 1 Int memory = 16 @@ -50,8 +52,8 @@ task VarDict { ~{true="var2vcf_paired.pl" false="var2vcf_valid.pl" defined(normalBam)} \ -N "~{tumorSampleName}~{"|" + normalSampleName}" \ ~{true="" false="-E" defined(normalBam)} \ - -M \ - -A \ + ~{true="-M" false="" outputCandidateSomaticOnly} \ + ~{true="-A" false="" outputAllVariantsAtSamePosition} \ -Q ~{mappingQuality} \ -d ~{minimumTotalDepth} \ -v ~{minimumVariantDepth} \